Cloak and Dagger: Alternative Immune Evasion and Modulation Strategies of Poxviruses

@inproceedings{Bidgood2015CloakAD,
  title={Cloak and Dagger: Alternative Immune Evasion and Modulation Strategies of Poxviruses},
  author={Susanna R. Bidgood and Jason Mercer and Yorgo Modis and Stephen Graham},
  booktitle={Viruses},
  year={2015}
}
As all viruses rely on cellular factors throughout their replication cycle, to be successful they must evolve strategies to evade and/or manipulate the defence mechanisms employed by the host cell. In addition to their expression of a wide array of host modulatory factors, several recent studies have suggested that poxviruses may have evolved unique mechanisms to shunt or evade host detection. These potential mechanisms include mimicry of apoptotic bodies by mature virions (MVs), the use of… CONTINUE READING
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