Clinicoradiologic characteristics of patients with lung adenocarcinoma harboring EML4-ALK fusion oncogene.

@article{Fukui2012ClinicoradiologicCO,
  title={Clinicoradiologic characteristics of patients with lung adenocarcinoma harboring EML4-ALK fusion oncogene.},
  author={Takayuki Fukui and Yasushi Yatabe and Yoshihisa Kobayashi and Kenji Tomizawa and Simon Ito and Shunzo Hatooka and Keitaro Matsuo and Tetsuya Mitsudomi},
  journal={Lung cancer},
  year={2012},
  volume={77 2},
  pages={319-25}
}
INTRODUCTION The fusion oncogene of echinoderm microtubule-associated protein like 4 (EML4) and anaplastic lymphoma kinase (ALK) defines a new molecular subset of non-small-cell lung cancer. We explored the EML4-ALK gene in a relatively large cohort and reviewed the clinicoradiologic background of the patients. METHODS We studied 720 patients with lung adenocarcinoma. The clinicopathological characteristics of each patient were compared among the subgroups stratified by the EML4-ALK gene… CONTINUE READING

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