Clinicopathological significance of non-small cell lung cancer with high prevalence of Oct-4 tumor cells

@inproceedings{Chen2012ClinicopathologicalSO,
  title={Clinicopathological significance of non-small cell lung cancer with high prevalence of Oct-4 tumor cells},
  author={Zhenguang Chen and Tao Wang and Lie Cai and Chunhua Su and Beilong Zhong and Yiyan Lei and Andy Peng Xiang},
  booktitle={Journal of experimental & clinical cancer research : CR},
  year={2012}
}
BACKGROUND Expression of the stem cell marker octamer 4 (Oct-4) in various neoplasms has been previously reported, but very little is currently known about the potential function of Oct-4 in this setting. The purpose of this study was to assess the prognostic value of Oct-4 expression after surgery in primary non-small cell lung cancer (NSCLC) and investigate its possible molecular mechanism. METHODS We measured Oct-4 expression in 113 NSCLC tissue samples and three cell lines by… CONTINUE READING
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