Clinicopathological features and treatment strategy for triple-negative breast cancer

@article{Yamamoto2010ClinicopathologicalFA,
  title={Clinicopathological features and treatment strategy for triple-negative breast cancer},
  author={Yutaka Yamamoto and Hirotaka Iwase},
  journal={International Journal of Clinical Oncology},
  year={2010},
  volume={15},
  pages={341-351}
}
Breast cancers are divided into at least 4 subtypes on the basis of gene expression profiles and expression of receptors (hormone receptors (HR) and HER2) as measured by immunohistochemistry. These subtypes have different prognoses and responses to treatments such as endocrine manipulation, anti-HER2 therapy, and chemotherapy. Triple-negative breast cancer (TNBC) is immunohistochemically defined as lacking estrogen and progesterone receptors and not overexpressing HER2. TNBC accounts for… CONTINUE READING
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