Corpus ID: 44217914

Clinicopathological factors associated to HER-2 status in a hospital-based sample of breast cancer patients in Puerto Rico.

@article{Ortiz2010ClinicopathologicalFA,
  title={Clinicopathological factors associated to HER-2 status in a hospital-based sample of breast cancer patients in Puerto Rico.},
  author={Ana P Ortiz and Orqu{\'i}dea Fr{\'i}as and Carmen I Gonz{\'a}lez-Keelan and Erick L Su{\'a}rez and David Cap{\'o} and Javier P{\'e}rez and Fernando Guiberteau Cabanillas and Edna M. Mora},
  journal={Puerto Rico health sciences journal},
  year={2010},
  volume={29 3},
  pages={
          265-71
        }
}
Breast cancer is the most common female malignancy in Puerto Rico. Cases with human epidermal growth factor receptor 2 (HER-2) oncoprotein overamplification are associated with aggressive clinical behavior. Given the limited availability of information for Puerto Rico, we aimed to evaluate the prevalence and clinical correlates of HER-2 gene overexpression among a hospital-based female population of breast cancer cases. We analyzed data from 1,049 female patients with invasive breast cancer… Expand
3 Citations
Breast cancer molecular subtypes and survival in a hospital-based sample in Puerto Rico
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This is the most comprehensive epidemiological study to date on the impact of hormone receptor expression subtypes in BC survival in Puerto Rico and consistent to results in other populations, the TN subtype and HER‐2+ tumors were associated with decreased survival. Expand
Application of FISH Technique in Evaluation of Equivocal Cases of HER2/neu in Breast Carcinoma
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In this study, HER2/neu was statistically inversely associated with both ER and PR receptors and is in inverse statistically significant correlation with estrogen and progesterone receptors while not statistically significant with age and histological types of tumors. Expand
Prevalence of breast and ovarian cancer subtypes in Hispanic populations from Puerto Rico
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The data suggests that OC and BC subtypes distribution in Hispanic populations from PR are in-line with national averages and provides an opportunity to further study this population separate from other US Hispanic populations. Expand

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