Clinicopathological behaviour of multiple oral dysplastic lesions compared with that of single lesions.

@article{Hamadah2010ClinicopathologicalBO,
  title={Clinicopathological behaviour of multiple oral dysplastic lesions compared with that of single lesions.},
  author={O Hamadah and Michaela L Goodson and Peter J. Thomson},
  journal={The British journal of oral & maxillofacial surgery},
  year={2010},
  volume={48 7},
  pages={503-6}
}
Oral precancerous lesions may be solitary or multifocal, the latter being difficult to manage because of extensive field change. The aim of this study was to characterise differences in clinicopathological features, proliferative labelling indexes for cyclin A, cyclin B1, and Ki67, and clinical outcome 5 years after laser resection in a group of patients presenting with single and multiple oral precancerous lesions. Ninety-six patients with 132 lesions (78 single and 18 multiple) were recruited… CONTINUE READING
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