Clinicopathological Significance of Maspin Expression in Breast Cancer

  title={Clinicopathological Significance of Maspin Expression in Breast Cancer},
  author={Mi-ja Lee and Chae-Hong Suh and Zhu-hu Li},
  booktitle={Journal of Korean medical science},
Maspin is a unique serine proteinase inhibitor that has tumor suppressor activity. It has been reported that maspin is expressed in normal human mammary epithelial cells and it is down-regulated during the progression of cancer. However, to date, there is very limited data on the clinical significance of maspin expression in human breast cancer. In this study, maspin expression was assessed immunohistochemically from 80 invasive ductal carcinoma (IDC) specimens of the breast. Also, maspin… CONTINUE READING


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  • CW Elston, IO Ellis
  • 2004

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