Clinicopathologic study of mixed adenoneuroendocrine carcinomas of hepatobiliary organs

@article{Harada2012ClinicopathologicSO,
  title={Clinicopathologic study of mixed adenoneuroendocrine carcinomas of hepatobiliary organs},
  author={Kenichi Harada and Yasunori Sato and Hiroko Kurimasa Ikeda and Hsu Maylee and Saya Igarashi and Atsushi Okamura and Shinji Masuda and Yasuni Nakanuma},
  journal={Virchows Archiv},
  year={2012},
  volume={460},
  pages={281-289}
}
Neuroendocrine neoplasms in hepatobiliary organs are very rare, but several cases of mixed adenoneuroendocrine carcinoma (MANEC) have been reported. In this study, we characterized the neuroendocrine component of biliary MANEC. A total of 274 cases of biliary cancer including 17 intrahepatic cholangiocarcinomas (CCs), 15 hepatic hilar CCs without preceding hepatobiliary disease, 55 hepatic hilar CCs with hepatolithiasis, 49 gallbladder cancers, 53 extrahepatic CCs, and 85 hepatocellular… CONTINUE READING