Clinicopathologic significance of histologic grade, pgp, and p53 expression in canine lymphoma.

@article{Dhaliwal2013ClinicopathologicSO,
  title={Clinicopathologic significance of histologic grade, pgp, and p53 expression in canine lymphoma.},
  author={Ravinder S. Dhaliwal and Barbara E. Kitchell and E. J. Ehrhart and Victor E Valli and Nikolaos Dervisis},
  journal={Journal of the American Animal Hospital Association},
  year={2013},
  volume={49 3},
  pages={175-84}
}
To characterize the expression of P-glycoprotein (Pgp) and p53 in different histologic grades of canine multicentric lymphosarcoma (LSA), 31 cases of LSA without prior treatment were studied. The expression levels of the Pgp and p53 proteins were evaluated for their clinicopathologic significance among standard histologic evaluation. Immunohistochemistry (IHC) was performed on formalin-fixed, paraffin-embedded archival samples of 31 previously untreated LSA cases to detect the expression of Pgp… CONTINUE READING
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