Clinicopathologic implications of the epidermal growth factor receptor, cyclooxygenase 2 expression, and human papillomavirus status in squamous cell carcinoma of the uterine cervix in the elderly.

@article{Giordano2011ClinicopathologicIO,
  title={Clinicopathologic implications of the epidermal growth factor receptor, cyclooxygenase 2 expression, and human papillomavirus status in squamous cell carcinoma of the uterine cervix in the elderly.},
  author={Giovanna Giordano and Tiziana D'adda and Barbara Dal Bello and Francesca Brigati and Alessandra Bersiga and Nicoletta Campanini and Roberto Berretta and Alba Rocco and Carla Merisio},
  journal={International journal of gynecological cancer : official journal of the International Gynecological Cancer Society},
  year={2011},
  volume={21 2},
  pages={
          337-48
        }
}
OBJECTIVES To find information on invasive squamous cervical carcinoma in the elderly, 110 invasive squamous cervical carcinomas obtained from 2 groups of patients (aged <60 and >60 years) were analyzed for human papillomavirus (HPV) status by polymerase chain reaction study, for immunohistochemical epidermal growth factor receptor (EGFR), cyclooxygenase 2 (Cox-2) expression, and clinicopathologic features. METHODS The HPV status and the expression of Cox-2 and EGFR in the younger and older… CONTINUE READING