Clinicopathologic and dysmorphic findings in recombinant chromosome 8 syndrome.

  title={Clinicopathologic and dysmorphic findings in recombinant chromosome 8 syndrome.},
  author={Thomas Michael Williams and Thomas S. McConnell and Francisco J. Mart{\'i}nez and Ann Cm Smith and Eva Sujansky},
  journal={Human pathology},
  volume={15 11},
Clinical records, autopsy reports, and microscopic slides from 11 infants with the recombinant 8 syndrome, an inherited abnormality of chromosome 8 affecting Hispanics from New Mexico and Colorado, were evaluated. A prevalence of cardiac and genitourinary anomalies was found, while few central nervous system abnormalities were observed. Dysmorphic features associated with recombinant 8 syndrome are presented, with descriptions of the inheritance pattern and recurrence risk. Because recombinant… CONTINUE READING