Clinicohistopathological correlations in juvenile localized scleroderma: studies on a subset of children with hypopigmented juvenile localized scleroderma due to loss of epidermal melanocytes.

@article{Sung2011ClinicohistopathologicalCI,
  title={Clinicohistopathological correlations in juvenile localized scleroderma: studies on a subset of children with hypopigmented juvenile localized scleroderma due to loss of epidermal melanocytes.},
  author={Joanne J Sung and Tina S Chen and Anita C. Gilliam and Timothy H McCalmont and Amy E. Gilliam},
  journal={Journal of the American Academy of Dermatology},
  year={2011},
  volume={65 2},
  pages={
          364-373
        }
}
BACKGROUND Localized scleroderma or morphea is a connective tissue disorder characterized by fibrosis of the skin and subcutaneous tissue. Excessive accumulation of collagen underlies the fibrosis, yet the pathogenesis is unknown. A subset of localized scleroderma/morphea, juvenile localized scleroderma (JLS), affects children and adolescents. OBJECTIVES The clinical and microscopic features of JLS have not been fully characterized. The goal is to better characterize the microscopic features… CONTINUE READING

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