Clinico-pathological features of postural hypotension in diabetic autonomic neuropathy.

  title={Clinico-pathological features of postural hypotension in diabetic autonomic neuropathy.},
  author={Kashif I Khawaja and Damien Walker and Sultan A Hayat and AndrewJ. M. Boulton and Rayaz A. Malik},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  volume={17 2},
We report the clinico-pathological features and management of a 49-year-old male with a 30-year history of Type 1 diabetes mellitus who had nephropathy (proteinuria 1.81 g/24 h, creatinine 136 micromol/l), proliferative retinopathy and severe somatic and autonomic neuropathy. A sural nerve biopsy demonstrated marked myelinated fibre loss with unmyelinated fibre degeneration and regeneration combined with extensive endoneurial microangiopathy. The management of the patient's blood pressure… CONTINUE READING