Clinico-Pathological Association of Delineated miRNAs in Uveal Melanoma with Monosomy 3/Disomy 3 Chromosomal Aberrations

@inproceedings{Venkatesan2016ClinicoPathologicalAO,
  title={Clinico-Pathological Association of Delineated miRNAs in Uveal Melanoma with Monosomy 3/Disomy 3 Chromosomal Aberrations},
  author={Nalini Venkatesan and J. R. Kanwar and Perinkulam Ravi Deepa and Vikas Khetan and Tamsyn M. Crowley and Rajeswari Raguraman and Ganesan Sugneswari and Pukhraj Rishi and Viswanathan Natarajan and Jyotirmay Biswas and Subramanium Krishnakumar and Zheng Li},
  booktitle={PloS one},
  year={2016}
}
PURPOSE To correlate the differentially expressed miRNAs with clinico-pathological features in uveal melanoma (UM) tumors harbouring chromosomal 3 aberrations among South Asian Indian cohort. METHODS Based on chromosomal 3 aberration, UM (n = 86) were grouped into monosomy 3 (M3; n = 51) and disomy 3 (D3; n = 35) by chromogenic in-situ hybridisation (CISH). The clinico-pathological features were recorded. miRNA profiling was performed in formalin fixed paraffin embedded (FFPE) UM samples (n… CONTINUE READING
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