Clinically significant azole cross‐resistance in Candida isolates from HIV‐positive patients with oral candidosis

@article{Cartledge1997ClinicallySA,
  title={Clinically significant azole cross‐resistance in Candida isolates from HIV‐positive patients with oral candidosis},
  author={Jonathan D. Cartledge and Jennifer Midgley and Brian George Gazzard},
  journal={AIDS},
  year={1997},
  volume={11},
  pages={1839–1844}
}
Objectives:To determine the proportion of fluconazole-resistant Candida albicans isolates that have clinically significant cross-resistance to itraconazole or ketoconazole, that is sufficient to result in failure of these agents at their standard doses (200 and 400 mg daily for 7 days, respectively). Methods:Seven hundred C. albicans isolates from HIV-positive patients with oral candidosis underwent susceptibility testing using a relative growth method, for which cut-off values corresponding to… Expand
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