Clinically meaningful changes in quantitative measures of asthma severity.

@article{Karras2000ClinicallyMC,
  title={Clinically meaningful changes in quantitative measures of asthma severity.},
  author={David J Karras and Maura Sammon and Carol A. Terregino and Bernard L. Lopez and Sharon K. Griswold and Gerald K Arnold},
  journal={Academic emergency medicine : official journal of the Society for Academic Emergency Medicine},
  year={2000},
  volume={7 4},
  pages={327-34}
}
OBJECTIVE To determine minimum clinically meaningful improvements in peak expiratory flow rate (PEFR) and dyspnea visual analog score (VAS) in patients with acute asthma exacerbation. METHODS Patients presenting to the emergency department (ED) with acute asthma exacerbation were eligible. The PEFR and VAS were assessed at presentation and after initial asthma therapy. During reassessment, subjects were asked to describe their asthma symptoms as "much better," "a little better," "no change… CONTINUE READING
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