Clinically Relevant Detection of Streptococcus pneumoniae with DNA-Antibody Nanostructures.

@article{Wang2017ClinicallyRD,
  title={Clinically Relevant Detection of Streptococcus pneumoniae with DNA-Antibody Nanostructures.},
  author={Jinping Wang and May Ching Leong and Eric Zhe Wei Leong and Win Sen Kuan and David Tai Leong},
  journal={Analytical chemistry},
  year={2017},
  volume={89 12},
  pages={6900-6906}
}
Streptococcus pneumoniae (SP) is a pathogenic bacterium and a major cause of community-acquired pneumonia that could be fatal if left untreated. Therefore, rapid and sensitive detection of SP is crucial to enable targeted treatment during SP infections. In this study, DNA tetrahedron (DNA TH) with a hollow structure is anchored on gold electrodes to construct an electrochemical immunosensor for rapid detection of pneumococcal surface protein A (PspA) peptide and SP lysate from synthetic and… CONTINUE READING
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