Clinical value of Tiam1-Rac1 signaling in primary gallbladder carcinoma.

  title={Clinical value of Tiam1-Rac1 signaling in primary gallbladder carcinoma.},
  author={Xilin Du and Shengzhi Wang and Jianguo Lu and Qing Wang and Nuan Song and Tao Yang and Rui Dong and L. F. Zang and Yuan Yang and Tao Wu and Chengguo Wang},
  journal={Medical oncology},
  volume={29 3},
Tiam1-Rac1 signaling plays an important role in the migration, invasion and metastasis of tumor cells. The aim of the present study was to clarify the clinical value of Tiam1 and Rac1 expression in primary gallbladder carcinoma (PGC). Eighty-six PGC tissues were evaluated by immunohistochemistry for Tiam1 and Rac1 expression. The association of Tiam1 and Rac1 expression with clinicopathological characteristics and the univariate survival analysis for the influence of Tiam1 and Rac1 expression… CONTINUE READING
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