Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis

@inproceedings{Huang2018ClinicalVO,
  title={Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis},
  author={Xiaojun Huang and Chaoqun Wang and Jinmin Sun and Jun Luo and Jiangzhou You and Linchuan Liao and Mingyuan Li},
  booktitle={Oncology letters},
  year={2018}
}
Gastric cancer (GC) is the fourth most common type of malignant tumor worldwide, and causes the second highest number of cancer-associated mortalities in 2012. Gastric tumorigenesis is a multistep and multifactorial process. In the present study, tissue microarray and immunohistochemistry analysis were used to detect cytotoxin-associated gene A (CagA), c-Met, phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) and Beclin-1 expression in 121 GC tumors and 120 normal gastric tissues. The… CONTINUE READING