Clinical utility of total HCV core antigen quantification: a new indirect marker of HCV replication.

@article{BouvierAlias2002ClinicalUO,
  title={Clinical utility of total HCV core antigen quantification: a new indirect marker of HCV replication.},
  author={Magali Bouvier-Alias and Keyur A. Patel and Harel Dahari and Stephanie Beaucourt and Patrick Larderie and Lawrence Mitchell Blatt and Christophe H{\'e}zode and Gaston Picchio and Daniel Dhumeaux and Avidan U Neumann and John McHutchison and Jean-Michel Pawlotsky},
  journal={Hepatology},
  year={2002},
  volume={36 1},
  pages={211-8}
}
Hepatitis C virus (HCV) RNA detection, viral load quantification, and HCV genotyping are widely used in clinical practice. Recently, the availability of an anticore antigen (Ag) monoclonal antibody allowed development of an enzyme-linked immunosorbent assay (ELISA) detecting and quantifying total HCV core Ag in peripheral blood of HCV-infected patients. The aims of the present study were to investigate the biologic significance of this new marker in HCV infection, to establish the intrinsic… CONTINUE READING

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