Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation.

@article{Ong2012ClinicalUO,
  title={Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation.},
  author={Frank Shih-Chang Ong and Joshua L. Deignan and Jane Zea-Chin Kuo and Kenneth E. Bernstein and Jerome I. Rotter and Wayne W. Grody and Kingshuk Das},
  journal={Pharmacogenomics},
  year={2012},
  volume={13 4},
  pages={
          465-75
        }
}
In the past decade, significant strides have been made in the area of cardiovascular pharmacogenomic research, with the discovery of associations between certain genotypes and drug-response phenotypes. While the motivations for personalized and predictive medicine are promising for patient care and support a model of health system efficiency, the implementation of pharmacogenomics for cardiovascular therapeutics on a population scale faces substantial challenges. The greatest obstacle to… 
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