Clinical utility of des-γ-carboxyprothrombin kinetics as a complement to radiologic response in patients with hepatocellular carcinoma undergoing transarterial chemoembolization.

@article{Park2012ClinicalUO,
  title={Clinical utility of des-γ-carboxyprothrombin kinetics as a complement to radiologic response in patients with hepatocellular carcinoma undergoing transarterial chemoembolization.},
  author={Won-Hyeong Park and Ju-Hyun Shim and Seungbong Han and Hyung-Jin Won and Yong-Moon Shin and Kang-Mo Kim and Young-Suk Lim and H Lee},
  journal={Journal of vascular and interventional radiology : JVIR},
  year={2012},
  volume={23 7},
  pages={927-36}
}
PURPOSE Serial α-fetoprotein (AFP) measurements are useful for assessing tumor responses to numerous therapies for hepatocellular carcinoma (HCC). This study tested the predictive value of changes in des-γ-carboxy prothrombin (DCP), in parallel with AFP, as an indicator of HCC response after transarterial chemoembolization. MATERIALS AND METHODS The study group consisted of 327 patients with HCC initially seropositive for DCP (≥ 40 mAU/mL) and/or AFP (≥ 100 ng/mL) who underwent repeated… CONTINUE READING