Clinical utility of contemporary molecular cytogenetics.

@article{Bejjani2008ClinicalUO,
  title={Clinical utility of contemporary molecular cytogenetics.},
  author={Bassem A. Bejjani and Lisa Gail Shaffer},
  journal={Annual review of genomics and human genetics},
  year={2008},
  volume={9},
  pages={
          71-86
        }
}
The development of microarray-based comparative genomic hybridization (array CGH) methods represents a critical new advance in molecular cytogenetics. This new technology has driven a technical convergence between molecular diagnostics and clinical cytogenetics, questioned our naïve understanding of the complexity of the human genome, revolutionized the practice of medical genetics, challenged conventional wisdom related to the genetic bases of multifactorial and sporadic conditions, and is… CONTINUE READING
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