Clinical utility and differential effects of prostaglandin analogs in the management of raised intraocular pressure and ocular hypertension

@inproceedings{Lee2010ClinicalUA,
  title={Clinical utility and differential effects of prostaglandin analogs in the management of raised intraocular pressure and ocular hypertension},
  author={Anne J. Lee and Peter Mccluskey},
  booktitle={Clinical ophthalmology},
  year={2010}
}
Prostaglandin analogs (PGA) are powerful topical ocular hypotensive agents available for the treatment of elevated intraocular pressure (IOP). Latanoprost 0.005% and travoprost 0.004% are prodrugs and analogs of prostaglandin F2alpha. Bimatoprost 0.03% is regarded as a prostamide, and debate continues as to whether it is a prodrug. The free acids of all 3 PGAs reduce IOP by enhancing uveoscleral and trabecular outflow via direct effects on ciliary muscle relaxation and remodeling of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 297 references

Intraocular pressurelowering effects of all commonly used glaucoma drugs: a meta-analysis of randomized clinical trials

  • R van der Valk, CA Webers, JS Schouten
  • 2005
Highly Influential
5 Excerpts

Latanoprost 0.005%) ophthalmic solution: prescribing information

  • Pfizer. Xalatan
  • Available online
  • 2009
Highly Influential
4 Excerpts

Intraocular pressurelowering effect of adding dorzolamide or latanoprost to timolol. A meta-analysis of randomized clinical trials

  • CA Webers, R van der Valk, JS Schouten
  • Ophthalmology
  • 2007
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…