Clinical usefulness of additional treatment with ezetimibe in patients with coronary artery disease on statin therapy. - From the viewpoint of cholesterol metabolism.-.

@article{Okada2011ClinicalUO,
  title={Clinical usefulness of additional treatment with ezetimibe in patients with coronary artery disease on statin therapy. - From the viewpoint of cholesterol metabolism.-.},
  author={Kozo Okada and Kazuo Kimura and Noriaki Iwahashi and Tomoyuki Endo and Hideo Himeno and Kazuki Fukui and Shunichi Kobayashi and Masato Shimizu and Yuji Iwasawa and Yukiko Morita and Atsushi Wada and Tomohiko Shigemasa and Yasuyuki Mochida and Tomoaki Shimizu and Reimin Sawada and Kazuaki Uchino and Satoshi Umemura},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2011},
  volume={75 10},
  pages={
          2496-504
        }
}
BACKGROUND Ezetimibe-plus-statin therapy has been reported to provide greater reduction in low-density lipoprotein cholesterol (LDL-C) level than statin monotherapy. The aim of the present study was to evaluate the relationship between LDL-C lowering effect and baseline cholesterol absorption and synthesis markers in patients with coronary artery disease (CAD). METHODS AND RESULTS A total of 171 patients with CAD whose LDL-C level was ≥ 100 mg/dl after treatment with atorvastatin (10mg/day… CONTINUE READING
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