Clinical use of the anion gap.

@article{Emmett1977ClinicalUO,
  title={Clinical use of the anion gap.},
  author={Michael Emmett and Robert G. Narins},
  journal={Medicine},
  year={1977},
  volume={56 1},
  pages={38-54}
}
The concepts underlying the clinical use of the anion gap (AG) and those disorders associated with its alteration are reviewed. A substantial increase in the AG usually indicates the presence of a metabolic acidosis, unless large doses of certain antibiotics or sodium salts of organic acids are being used. The etiology, pathogenesis and diagnosis of high AG metabolic acidoses are discussed. Stress is placed upon the utility of the AG in defining the cause of the acidosis, and as a guide to… CONTINUE READING

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