Clinical trials of rotavirus vaccines in Europe.


Clinical trials of a live oral candidate rotavirus vaccine were started in 1982 and soon demonstrated that severe rotavirus disease can be prevented by vaccination. The first bovine candidate vaccine was withdrawn because of inconsistent efficacy, and studies of a rhesus rotavirus vaccine were initiated. A field trial of rhesus-human reassortant tetravalent… (More)


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@article{Vesikari2006ClinicalTO, title={Clinical trials of rotavirus vaccines in Europe.}, author={Timo Vesikari and Carlo Giaquinto and H. I. Huppertz}, journal={The Pediatric infectious disease journal}, year={2006}, volume={25 1 Suppl}, pages={S42-7} }