Clinical trials of homoeopathy.

@article{Kleijnen1991ClinicalTO,
  title={Clinical trials of homoeopathy.},
  author={Jos Kleijnen and Paul G. Knipschild and Gerben ter Riet},
  journal={British Medical Journal},
  year={1991},
  volume={302},
  pages={316 - 323}
}
OBJECTIVE--To establish whether there is evidence of the efficacy of homoeopathy from controlled trials in humans. DESIGN--Criteria based meta-analysis. Assessment of the methodological quality of 107 controlled trials in 96 published reports found after an extensive search. Trials were scored using a list of predefined criteria of good methodology, and the outcome of the trials was interpreted in relation to their quality. SETTING--Controlled trials published world wide. MAIN OUTCOME MEASURES… 

A systematic review of the quality of homeopathic clinical trials

TLDR
The quality of clinical-trial research in homeopathy was worse and only slightly improved in more recent years compared to research on conventional therapies, and many of these problems are correctable even within a "holistic" paradigm.

Homoeopathy and hayfever

  • A. FrewC. CorriganA. B. Kay
  • Medicine
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 1991
Sir, There is current interest in methodological analysis of clinical trials of homoeopathy [1]. When this form of treatment was reviewed in a recent article in the British Medical Journal high

Clinical Studies on Homoeopathy. The Problem of a Useful Design

TLDR
Clinical studies on homoeopathy should be planned in co-operation between homoeopathic practitioners and university clinics, because this allows for a maximum methodological standard and also for the possibility of publication in distinguished journals with a high impact factor, which usually are not available for homoeopaths.

Randomised placebo-controlled trials of individualised homeopathic treatment: systematic review and meta-analysis

TLDR
Medicines prescribed in individualised homeopathy may have small, specific treatment effects and the low or unclear overall quality of the evidence prompts caution in interpreting the findings.

Efficacy of homeopathic arnica: a systematic review of placebo-controlled clinical trials.

TLDR
The claim that homeopathic arnica is efficacious beyond a placebo effect is not supported by rigorous clinical trials, and most of these studies were burdened with severe methodological flaws.

Controlled clinical studies of homeopathy.

  • R. Mathie
  • Medicine
    Homeopathy : the journal of the Faculty of Homeopathy
  • 2015
...

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TLDR
The proportion of cases who recovered within 48 h of treatment was greater among the active drug group than among the placebo group, and the result cannot be explained given the present state of knowledge, but it calls for further rigorously designed clinical studies.

Double-blind trial comparing the effectiveness of the homeopathic preparation Galphimia potentiation D6, Galphimia dilution 10(-6) and placebo on pollinosis.

TLDR
In a controlled randomized strictly double-blind trial with 164 patients the effectiveness of homeopathically prepared Galphimia D6, a conventional Galphimsia dilution 10(-6) and a placebo was investigated for the therapy of pollinosis.

[Treatment of irritable colon. A multicenter placebo-controlled double-blind study in general practice].

TLDR
The trial shows that it is possible to obtain objective results on the basis of the patients' judgment (rating scales with low information content) and both groups with active medication differed trivially but showed a marked superiority to the placebo group.

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TLDR
This paper reports the results of a pilot study in which 41 patients with rheumatoid arthritis were treated with high doses of salicylate, 3.9 g per day, and the results compared with a further 54 similar patients treated with homoeopathy, which found the patients who received homoeopathic treatment did better than those who received salicYLate.

Homoeopathy and its Potential Role in Agriculture—A Critical Review

TLDR
The conclusion is that despite a great deal of experimental and clinical work there is only a little evidence to suggest that homoeopathic treatment of disease is effective.

Homoeopathic therapy in rheumatoid arthritis: evaluation by double-blind clinical therapeutic trial.

TLDR
There was a significant improvement in subjective pain, articular index, stiffness and grip strength in those patients receiving homoeopathic remedies whereas there was no significant change in the patients who received placebo.
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