Clinical trials of antihypertensives: Nature of control and design

Abstract

This paper reviews the critical issues in the control and design of antihypertension (anti-HT) clinical trials. The international guidelines and current clinical and biostatistical practices were reviewed for relevant clinical, design, end-point assessments and regulatory issues. The results are grouped mainly into ethical, protocol and assessment issues… (More)
DOI: 10.4103/0253-7613.75659

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