Clinical trials in coronary angiogenesis: issues, problems, consensus: An expert panel summary.

@article{Simons2000ClinicalTI,
  title={Clinical trials in coronary angiogenesis: issues, problems, consensus: An expert panel summary.},
  author={Michael Simons and Robert Ogden Bonow and Nicolas A. F. Chronos and David J Cohen and Frank J. Giordano and H Kirk Hammond and Roger J. Laham and William Pui Lum Li and Matthew Pike and Frank W Sellke and Thomas J. Stegmann and James E. Udelson and Todd K. Rosengart},
  journal={Circulation},
  year={2000},
  volume={102 11},
  pages={
          E73-86
        }
}
The rapid development of angiogenic growth factor therapy for patients with advanced ischemic heart disease over the last 5 years offers hope of a new treatment strategy based on generation of new blood supply in the diseased heart. However, as the field of therapeutic coronary angiogenesis is maturing from basic and preclinical investigations to clinical trials, many new and presently unresolved issues are coming into focus. These include in-depth understanding of the biology of angiogenesis… CONTINUE READING

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