Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis

@inproceedings{Legocki2015ClinicalTP,
  title={Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis},
  author={Laurie Jo Legocki and William J Meurer and Shirley M. Frederiksen and R. J. Lewis and Valerie L Durkalski and Donald A. Berry and William G. Barsan and Michael D Fetters},
  booktitle={BMC medical ethics},
  year={2015}
}
BACKGROUND In an adaptive clinical trial (ACT), key trial characteristics may be altered during the course of the trial according to predefined rules in response to information that accumulates within the trial itself. In addition to having distinguishing scientific features, adaptive trials also may involve ethical considerations that differ from more traditional randomized trials. Better understanding of clinical trial experts' views about the ethical aspects of adaptive designs could assist… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 7 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
7 Extracted Citations
31 Extracted References
Similar Papers

Similar Papers

Loading similar papers…