Clinical trial of combination chemotherapy and specific active immunotherapy in disseminated melanoma.

@article{Newlands1976ClinicalTO,
  title={Clinical trial of combination chemotherapy and specific active immunotherapy in disseminated melanoma.},
  author={Edward Stewart Newlands and C-J. Oon and J. Trevor Roberts and Peter T. Elliott and Richard F. Mould and Christopher M. Topham and Franklin F. Madden and Kelly A Newton and Gerald Westbury},
  journal={British Journal of Cancer},
  year={1976},
  volume={34},
  pages={174 - 179}
}
Fifty-six patients with disseminated malignant melanoma were randomly allocated to two treatment groups. The first group C received combination chemotherapy consisting of DTIC and ICRF 159. The second group (C+I) received the same chemotherapy but were also immunized with 2 X 10(7) irradiated allogeneic melanoma cells mixed with 50 mug of percutaneous BCG. The survival rates in both treatment groups C and (C+I) were not significantly different, and only minor enhancement of the chemotherapy was… CONTINUE READING
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