Clinical trial evaluating the efficacy and safety of cyclosporine in dogs with atopic dermatitis.

@article{Steffan2005ClinicalTE,
  title={Clinical trial evaluating the efficacy and safety of cyclosporine in dogs with atopic dermatitis.},
  author={J. Greg Steffan and C. Parks and Wolfgang Seewald},
  journal={Journal of the American Veterinary Medical Association},
  year={2005},
  volume={226 11},
  pages={1855-63}
}
OBJECTIVE To determine efficacy and safety of cyclosporine in the treatment of atopic dermatitis among dogs in North America. DESIGN Randomized controlled (phase 1) and open-label (phase 2) trials. ANIMALS 268 dogs with atopic dermatitis. PROCEDURE In phase 1, dogs were randomly assigned to be treated with cyclosporine (5 mg/kg [2.3 mg/Ib], PO, q 24 h) or a placebo. In phase 2, all dogs were treated with cyclosporine for 16 weeks. Frequency of cyclosporine administration was decreased if… CONTINUE READING

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