Clinical trial and in vitro study investigating topical application of Zataria multiflora Boiss. and Matricaria chamomilla extracts for androgenetic alopecia

  title={Clinical trial and in vitro study investigating topical application of Zataria multiflora Boiss. and Matricaria chamomilla extracts for androgenetic alopecia},
  author={Anoosheh Sharifan and Ashraf Hajhoseini and M. Bakhtiari},
  journal={Cogent Medicine},
Abstract This study was intended to evaluate the hair growth activity of Zataria multiflora Boiss. (ZM) and Matricaria chamomilla (MC) for androgenetic alopecia following a six-month clinical trial. In vitro studies were conducted to measure the inhibitory effects of MC and ZM against 5α-reductase (5αR). In this regard, five samples were prepared: NADPH + enzyme + testosterone + extract (n = 2); enzyme blank (n = 1); positive and negative controls (n = 2). Thereafter, 60 patients with… 


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