Clinical translation of folate receptor-targeted therapeutics.

  title={Clinical translation of folate receptor-targeted therapeutics.},
  author={Lesheng Teng and Jing Xie and Lirong Teng and Robert J Lee},
  journal={Expert opinion on drug delivery},
  volume={9 8},
INTRODUCTION Folate receptor-α (FR-α) has been established as a membrane marker for ovarian cancer. In addition, it is frequently overexpressed in other major types of epithelial tumors. FR-α-based tumor-targeted therapy and drug carriers have been an active area of laboratory research for more than 20 years. Recently, there has been a great increase in the… CONTINUE READING