Clinical study of genomic drivers in pancreatic ductal adenocarcinoma

Background:Pancreatic ductal adenocarcinoma (PDA) is a lethal cancer with complex genomes and dense fibrotic stroma. This study was designed to identify clinically relevant somatic aberrations in pancreatic cancer genomes of patients with primary and metastatic disease enrolled and treated in two clinical trials.Methods:Tumour nuclei were flow sorted prior… CONTINUE READING