Clinical study for alleviating opiate drug psychological dependence by a method of ablating the nucleus accumbens with stereotactic surgery.

@article{Gao2003ClinicalSF,
  title={Clinical study for alleviating opiate drug psychological dependence by a method of ablating the nucleus accumbens with stereotactic surgery.},
  author={Guodong Gao and Xuelian Wang and Shiming He and Weixin Li and Qingfeng Wang and Qinchuan Liang and Yaqun Zhao and Fang Hou and Ling Chen and Aining Li},
  journal={Stereotactic and functional neurosurgery},
  year={2003},
  volume={81 1-4},
  pages={96-104}
}
The aim of this study was to explore a new way of treating drug addiction by ablating the nucleus accumbens (NAC), which has a close relationship with drug-induced psychological dependence, using stereotactic surgery, blocking the mesocorticolimbic dopamine circuit, alleviating craving for drugs and lowering the relapse rate after detoxification. On the basis of animal experiments, stereotactic surgery was performed in 28 patients by making a lesion in the NAC bilaterally to treat opiate drug… CONTINUE READING