Clinical spectrum of levodopa‐induced complications

@article{Aquino2015ClinicalSO,
  title={Clinical spectrum of levodopa‐induced complications},
  author={Camila Catherine Aquino and Susan H. Fox},
  journal={Movement Disorders},
  year={2015},
  volume={30}
}
  • C. Aquino, S. Fox
  • Published 1 January 2015
  • Psychology, Medicine, Biology
  • Movement Disorders
The first years of Parkinson disease (PD) treatment are marked by good and sustained responses to dopaminergic therapy. With disease progression and longer exposure to levodopa (l‐dopa), patients develop a range of l‐dopa–induced complications that include motor and non‐motor symptoms. Motor complications include motor fluctuations, characterized by periods of reduced benefit from the medication, and l‐dopa–induced dyskinesia, characterized by emergence of hyperkinetic involuntary movements… 
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