Clinical spectrum of cortical dysplasia in childhood: diagnosis and treatment issues.

@article{Whiting1999ClinicalSO,
  title={Clinical spectrum of cortical dysplasia in childhood: diagnosis and treatment issues.},
  author={Sharon Whiting and Michael S. Duchowny},
  journal={Journal of child neurology},
  year={1999},
  volume={14 12},
  pages={759-71}
}
Disorders of cortical development form a spectrum of lesions produced by insults to the developing neocortex. These conditions typically first manifest in childhood with epilepsy, developmental delay, and focal neurologic signs. Although the clinical and electrophysiologic findings are often nonspecific, high-resolution magnetic resonance imaging facilitates diagnosis during life, and assists in delineating specific clinical syndromes. While many patients are dysmorphic and severely affected by… CONTINUE READING