Clinical spectrum of CADASIL and the effect of cardiovascular risk factors on phenotype: study in 200 consecutively recruited individuals.

@article{AdibSamii2010ClinicalSO,
  title={Clinical spectrum of CADASIL and the effect of cardiovascular risk factors on phenotype: study in 200 consecutively recruited individuals.},
  author={Poneh Adib-Samii and Glen Brice and Roswell J Martin and Hugh S. Markus},
  journal={Stroke},
  year={2010},
  volume={41 4},
  pages={630-4}
}
BACKGROUND AND PURPOSE Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is an inherited arteriopathy with clinical features that include recurrent lacunar stroke, migraine, and cognitive impairment. For reasons that remain unclear, there is great variability in the clinical expression of CADASIL, both between and within families. This study examined the clinical phenotype as well as any associations with risk factors and genotype in a large… CONTINUE READING

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