Clinical significance of vasculogenic mimicry in human gliomas

  title={Clinical significance of vasculogenic mimicry in human gliomas},
  author={Xiao-mei Liu and Qing-ping Zhang and Yong-gao Mu and Xiang-hen Zhang and K E Sai and Jesse Chung-sean Pang and Ho Keung Ng and Zhongping Chen},
  booktitle={Journal of Neuro-Oncology},
Vasculogenic mimicry (VM) is known as non-endothelial tumor cell-lined microvascular channels in aggressive tumors. We have previously found the presence of VM in high-grade gliomas. In this study, we aimed to identify VM patterns in gliomas and to explore their clinical significance. Tumor samples as well as their detailed clinical/prognostic data were collected from 101 patients. Vasculogenic mimicry in the glioma samples was determined by dual staining for endothelial marker CD34 and… CONTINUE READING
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