Clinical significance of vascular endothelial growth factor-C and vascular endothelial growth factor receptor 3 in patients with T1 lung adenocarcinoma.

@article{Kojima2005ClinicalSO,
  title={Clinical significance of vascular endothelial growth factor-C and vascular endothelial growth factor receptor 3 in patients with T1 lung adenocarcinoma.},
  author={Hiroshi Kojima and Noriharu Shijubo and Gen Yamada and Shingo Ichimiya and Shosaku Abe and Masaaki Satoh and Noriyuki Sato},
  journal={Cancer},
  year={2005},
  volume={104 8},
  pages={
          1668-77
        }
}
BACKGROUND Vascular endothelial growth factor-C (VEGF-C) plays an important role in lymphangiogenesis and activates VEGF receptor-3 (VEGFR-3). Lymphatic spread is an important prognostic factor in patients with lung adenocarcinoma. The aim of the current study was to determine whether the expression of VEGF-C and VEGFR-3 correlates with clinicopathologic factors and prognosis in patients with TNM classification T1 lung adenocarcinoma. METHODS The authors conducted a retrospective review of… CONTINUE READING
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