Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma.

@article{Furudoi2002ClinicalSO,
  title={Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma.},
  author={Akira Furudoi and Shinji Tanaka and Ken Haruma and Yasuhiko Kitadai and Masaharu Yoshihara and Kazuaki Chayama and Fumio Shimamoto},
  journal={Oncology},
  year={2002},
  volume={62 2},
  pages={157-66}
}
AIM Vascular endothelial growth factor C (VEGF-C) is known to be associated with the development of the lymphatic vascular system. The aim of this study was to elucidate the clinical significance of VEGF-C expression and microvessel density (MVD) at the deepest invasive site in advanced colorectal carcinoma (CRC). METHODS 152 patients who had undergone surgical resection for advanced CRC entered this study. VEGF-C expression was examined immunohistochemically with anti-VEGF-C polyclonal… CONTINUE READING

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