Clinical significance of the WHO grades of follicular lymphoma in a population-based cohort of 505 patients with long follow-up times.

@article{Wahlin2012ClinicalSO,
  title={Clinical significance of the WHO grades of follicular lymphoma in a population-based cohort of 505 patients with long follow-up times.},
  author={Bj{\"o}rn Engelbrekt Wahlin and Olav Erich Yri and Eva K Kimby and Harald H. Holte and Jan Delabie and Erlend Smeland and Christer Sundstr{\"o}m and Birger Christensson and Birgitta Sander},
  journal={British journal of haematology},
  year={2012},
  volume={156 2},
  pages={225-33}
}
The prognostic value of grading follicular lymphoma has been debated since the 1980s. There is consensus that World Health Organization (WHO) grades 1 and 2 are indolent, but not whether grades 3A or 3B are aggressive. We retrospectively reviewed the follicular lymphoma diagnoses according to the 2008 WHO classification in all diagnostic specimens from a population-based cohort of 505 patients with a median follow-up time of 10·0years (range, 4·6-16·0). After excluding 43 patients with… CONTINUE READING
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