Clinical significance of serum autoantibodies in patients with NAFLD: results from the nonalcoholic steatohepatitis clinical research network.

@article{Vuppalanchi2012ClinicalSO,
  title={Clinical significance of serum autoantibodies in patients with NAFLD: results from the nonalcoholic steatohepatitis clinical research network.},
  author={Raj Vuppalanchi and Robert J Gould and Laura Wilson and Aynur Unalp-Arida and O William Cummings and Naga Chalasani and Kris V. Kowdley},
  journal={Hepatology international},
  year={2012},
  volume={6 1},
  pages={379-85}
}
PURPOSE Some studies have suggested that autoantibodies might define a subcategory and phenotype of nonalcoholic fatty liver disease (NAFLD) associated with advanced histological features. We evaluated the relationship between the presence of serum autoantibodies and liver histology in a large cohort of well-characterized patients with NAFLD. METHODS A total of 864 NAFLD patients participating in two prospective multicentre clinical studies underwent testing for serum autoantibodies within 24… CONTINUE READING
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