Clinical significance of plasma endostatin in acute myeloid leukemia/myelodysplastic syndrome.

@article{Lai2002ClinicalSO,
  title={Clinical significance of plasma endostatin in acute myeloid leukemia/myelodysplastic syndrome.},
  author={Raymond Lai and Elihu E Estey and Yu Shen and Simona X Despa and Hagop A Kantarjian and Miloslav E Beran and Taghi Maushouri and Robert C Quackenbuch and Micheal Keating and Maher Albitar},
  journal={Cancer},
  year={2002},
  volume={94 1},
  pages={14-7}
}
BACKGROUND Endostatin, a C-terminal fragment of collagen XVIII, is an endogenous angiogenesis inhibitor. While endostatin is being investigated for its usefulness in treating solid tumors, its significance in hematologic malignancies is unknown. METHODS The authors evaluated plasma endostatin (PE) levels using an enzyme linked immunoassay in 71 patients with acute myeloid leukemia (AML) and 43 patients with myelodysplastic syndrome (MDS), and correlated PE with various clinical parameters… CONTINUE READING
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