Clinical significance of plasma chlorpromazine levels. II. Plasma levels of the drug, some of its metabolites and prolactin in patients receiving long-term phenothiazine treatment.

@article{Kolakowska1976ClinicalSO,
  title={Clinical significance of plasma chlorpromazine levels. II. Plasma levels of the drug, some of its metabolites and prolactin in patients receiving long-term phenothiazine treatment.},
  author={T. Kolakowska and David H. Wiles and Michael G Gelder and Alan McNeilly},
  journal={Psychopharmacology},
  year={1976},
  volume={49 1},
  pages={101-7}
}
Plasma levels of chlorpromazine (CPZ), 3 of its metabolites and prolactin were measured repeatedly in 18 chronic schizophrenic patients. The patients were studied while on chronic phenothiazine medication (chlorpromazine in 8, other phenothiazines in 10), during 4-6 weeks on placebo and during 6-12 weeks of CPZ treatment. The findings were compared with… CONTINUE READING