Clinical significance of micrometastases in axillary lymph nodes assessed by reverse transcription-polymerase chain reaction in breast cancer patients.

@article{Masuda2000ClinicalSO,
  title={Clinical significance of micrometastases in axillary lymph nodes assessed by reverse transcription-polymerase chain reaction in breast cancer patients.},
  author={N Masuda and Y Tamaki and I Sakita and M Ooka and T Ohnishi and M Kadota and N Aritake and K Okubo and M Monden},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2000},
  volume={6 11},
  pages={4176-85}
}
  • N Masuda, Y Tamaki, +6 authors M Monden
  • Published 2000 in
    Clinical cancer research : an official journal of…
We evaluated the clinical significance of micrometastases in axillary lymph nodes (AxLNs) of breast cancer patients for prediction of prognosis. Archived formalin-fixed paraffin-embedded AxLN specimens from 129 node-negative breast cancer patients diagnosed by routine H&E staining between 1986 and 1990 were subjected to carcinoembryonic antigen-specific reverse transcription-PCR analysis. Micrometastases were detected in 40 of 129 (31.0%) node-negative breast cancer patients. After a median… CONTINUE READING