Clinical significance of microRNA-21 as a biomarker in each Dukes' stage of colorectal cancer.

  title={Clinical significance of microRNA-21 as a biomarker in each Dukes' stage of colorectal cancer.},
  author={Yoshihisa Fukushima and Hisae Iinuma and Mitsuo Tsukamoto and Keiji Matsuda and Yojiro Hashiguchi},
  journal={Oncology reports},
  volume={33 2},
The potential value of microRNAs (miRNAs) as prognostic biomarkers are of interest. It is known that microRNA-21 (miR-21) is implicated in the promotion, proliferation and progression of several types of human cancers. However, the prognostic significance of miR-21 in each tumor stage of colorectal cancer (CRC) remains elusive. The objective of this study was to clarify the prognostic value of miR-21 for CRC patients at each tumor stage. The expression levels of miR-21 in the tumor tissues and… CONTINUE READING
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