Clinical significance of long noncoding RNA SPRY4-IT1 in melanoma patients.

  title={Clinical significance of long noncoding RNA SPRY4-IT1 in melanoma patients.},
  author={Teng Liu and Song-Ke Shen and Jian-Gui Xiong and Yuan Xu and Han-qi Zhang and Hai-jun Liu and Zheng-Gen Lu},
  journal={FEBS open bio},
  volume={6 2},
Long noncoding RNA SPRY4-IT1 has been reported to promote melanoma cell growth and invasion, and to block apoptosis. The purpose of this study was to investigate the clinical significance of SPRY4-IT1 in patients with malignant melanoma. The relative expression levels of SPRY4-IT1 were measured in plasma samples from 70 patients and 79 healthy controls by quantitative reverse transcriptase polymerase chain reaction. SPRY4-IT1 expression is high in melanoma patients but low in healthy controls… CONTINUE READING
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